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Selected publications (* co-first author; # co-corresponding author):
  1. Jung, I.*, Schmitt, A.*, Diao, Y.*, Yang, D., Chiang, Z., Chan, M., Tan, C., Barr, C.L., Li, B., Kuan, S., Kim, D., and Ren, B. A compendium of promoter-centered long-range chromatin interactions in 27 human tissues and cell types. (under review in Nature)
  2. Li, B.*, Diao, Y.*, and Ren, B. CRISPR-web: a comprehensive CRISPR design framework. (manuscript in preparation)
  3. Chen, X., Wan, J., Yu, B., Diao, Y.#, and Zhang, W.# (2018) PIP5K1α promotes myogenic differentiation via AKT activation and calcium release. Stem Cell Res Ther. 9 (1), 33
  4. An, Y.*, Wang, G.*, Diao, Y.*, Long, Y., Fu, X., Weng, M., Zhou, L., Sun, K., Cheung, T. H., Ip, N., Sun, H., Wang, H., and Wu, Z., (2017). A Molecular Switch Regulating the Cell Fate Choice Between Muscle Progenitor Cells and Brown Adipocytes. Dev Cell. 41, 382-391.
  5. Diao, Y., Fang, R., Li, B., Meng, Z., Yu, J., Qiu, Y., Lin, K.C., Huang, H., Liu, T., Marina, R.J., Jung, I., Shen, Y., Guan, K.L., and Ren, B. (2017). A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. Nat Methods.
  6. Diao, Y., Li, B., Meng, Z., Jung, I., Lee, A.Y., Dixon, J., Maliskova, L., Guan, K.L., Shen, Y., and Ren, B. (2016). A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. Genome Res. 26, 397-405.
  7. Diao, Y., Guo, X., Jiang, L., Wang, G., Zhang, C., Wan, J., Jin, Y., and Wu, Z. (2014). miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma. J Biol Chem 289, 529-539.
  8. Diao, Y., Guo, X., Li, Y., Sun, K., Lu, L., Jiang, L., Fu, X., Zhu, H., Sun, H., Wang, H., and Wu, Z. (2012). Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Cell Stem Cell 11, 231-241.
  9. Diao, Y., Liu, W., Wong, C.C., Wang, X., Lee, K., Cheung, P.Y., Pan, L., Xu, T., Han, J., Yates, J.R., 3rd, Zhang, M., and Wu, Z. (2010). Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding. Proc Natl Acad Sci U S A 107, 20974-20979.
  10. Diao, Y., Wang, X., and Wu, Z. (2009). SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway. Mol Cell Biol 29, 5084-5093.

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307 Research Drive, 
373 Nanaline Duke Building, Box 3709
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Duke University School of Medicine
Durham, NC 27710
Email: diaolab@duke.edu
Telephone: 919-684-7090
Fax: 919-684-8090
If you are a Duke CMB, DSCB, and UPGG graduate student and you are interested in gene regulation, chromatin, single-cell genomics, stem cell, regeneration, aging, cancer research, genomic methods development, bioinformatics and computational biology, please contact us to set up a rotation!
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